Endothelin-1 promotes survival and chemoresistance in chronic lymphocytic leukemia B cells through ETA receptor.
The endothelin axis, comprising endothelins (ET-1, ET-2 and ET-3) and their receptors (ET(A)R and ETBR), has emerged as relevant player in tumor growth and metastasis. Here, we investigated the involvement of ET-1/ET(A)R axis in chronic lymphocytic leukemia (CLL). CLL cells expressed higher levels o...
প্রধান লেখক: | , , , , , , , , , , , , , , , , , |
---|---|
বিন্যাস: | প্রবন্ধ |
ভাষা: | English |
প্রকাশিত: |
Public Library of Science (PLoS)
2014-01-01
|
মালা: | PLoS ONE |
অনলাইন ব্যবহার করুন: | http://europepmc.org/articles/PMC4046988?pdf=render |