Spatial proteomics reveals phenotypic and functional differences in T cell and macrophage subsets during villitis of unknown etiology

Abstract Villitis of unknown etiology (VUE) is a prevalent inflammatory pathology of the placenta characterized by infiltration of maternal T cells and accumulation of fetal macrophages into chorionic villi. VUE is associated with a variety of adverse clinical outcomes, including fetal growth restri...

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Bibliographic Details
Main Authors: Petra K. Lothert, Bohdana Fedyshyn, Sylvie Girard, Rana Chakraborty, Andrew P. Norgan, Elizabeth Ann L. Enninga
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-51545-2