Pharmaceutical Cocrystal Development of TAK-020 with Enhanced Oral Absorption

Pharmaceutical Cocrystal Development of TAK-020 with Enhanced Oral Absorption

The objective of this study was to improve the solubility of poorly water-soluble drugs by pharmaceutical cocrystal engineering techniques and select the best pharmaceutical forms with high solubility and solubilized formulations for progress from the early discovery stage toward the clinical stage....

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Bibliographic Details
Main Authors: Kouya Kimoto, Mitsuo Yamamoto, Masatoshi Karashima, Miyuki Hohokabe, Junpei Takeda, Katsuhiko Yamamoto, Yukihiro Ikeda
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Crystals
Subjects:
cocrystal
poorly soluble drug
crystal engineering
solubilized formulation
absorption improvement
Online Access:https://www.mdpi.com/2073-4352/10/3/211

Internet

https://www.mdpi.com/2073-4352/10/3/211

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