Yishen Qingli Heluo Granule Ameliorates Renal Dysfunction in 5/6 Nephrectomized Rats by Targeting Gut Microbiota and Intestinal Barrier Integrity

Yishen Qingli Heluo Granule Ameliorates Renal Dysfunction in 5/6 Nephrectomized Rats by Targeting Gut Microbiota and Intestinal Barrier Integrity

Chronic kidney disease (CKD) is often accompanied with imbalanced gut microbiota and impaired intestinal barrier. Hence, efforts to ameliorate renal dysfunction by manipulating gut microbial ecosystem are underway. Yishen Qingli Heluo granule (YQHG) is a representative traditional Chinese medicine (...

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Bibliographic Details
Main Authors: Xian Sun, Jie Chen, Yiting Huang, Sha Zhu, Shuaishuai Wang, Zijing Xu, Junfeng Zhang, Wei Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Pharmacology
Subjects:
chronic kidney disease
yishen qingli heluo granule
gut microbiota
intestinal barrier
microbial translocation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.858881/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.858881/full

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