In vivo Visualization of M2 Macrophages in the Myocardium After Myocardial Infarction (MI) Using 68Ga-NOTA-Anti-MMR Nb: Targeting Mannose Receptor (MR, CD206) on M2 Macrophages

In vivo Visualization of M2 Macrophages in the Myocardium After Myocardial Infarction (MI) Using 68Ga-NOTA-Anti-MMR Nb: Targeting Mannose Receptor (MR, CD206) on M2 Macrophages

Introduction and ObjectivesWound healing after myocardial infarction (MI) is a dynamic and complex multiple phase process, and a coordinated cellular response is required for proper scar formation. The current paradigm suggests that pro-inflammatory monocytes infiltrate the MI zone during the initia...

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Bibliographic Details
Main Authors: Zohreh Varasteh, Miriam Braeuer, Sarajo Mohanta, Anna-Lena Steinsiek, Andreas Habenicht, Negar Omidvari, Geoffrey J. Topping, Christoph Rischpler, Wolfgang A. Weber, Hendrik B. Sager, Geert Raes, Sophie Hernot, Markus Schwaiger
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
myocardial infarction
inflammation
M2 macrophages
reparative phase
PET
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.889963/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.889963/full

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