Clinical molecular subtyping reveals intrinsic mesenchymal reprogramming in gastric cancer cells

Clinical molecular subtyping reveals intrinsic mesenchymal reprogramming in gastric cancer cells

Abstract The mesenchymal cancer phenotype is known to be clinically related to treatment resistance and a poor prognosis. We identified gene signature-based molecular subtypes of gastric cancer (GC, n = 547) based on transcriptome data and validated their prognostic and predictive utility in multipl...

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Main Authors: Eunji Jang, Min-Kyue Shin, Hyunki Kim, Joo Yeon Lim, Jae Eun Lee, Jungmin Park, Jungeun Kim, Hyeseon Kim, Youngmin Shin, Hye-Young Son, Yoon Young Choi, Woo Jin Hyung, Sung Hoon Noh, Jin-Suck Suh, Ji-Yong Sung, Yong-Min Huh, Jae-Ho Cheong
Format: Article
Language:English
Published: Nature Publishing Group 2023-05-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-00989-z

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https://doi.org/10.1038/s12276-023-00989-z

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