Case Report: Arterial Wall Inflammation in Atherosclerotic Cardiovascular Disease is Reduced by Olamkicept (sgp130Fc)

Case Report: Arterial Wall Inflammation in Atherosclerotic Cardiovascular Disease is Reduced by Olamkicept (sgp130Fc)

Inflammation is a strong driver of atherosclerotic cardiovascular disease (ASCVD). There is a large unmet need for therapies that prevent or reduce excessive inflammation while avoiding systemic immunosuppression. We showed previously that selective inhibition of pro-inflammatory interleukin-6 (IL-6...

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Bibliographic Details
Main Authors: Dominik M. Schulte, Georg H. Waetzig, Harald Schuett, Marlies Marx, Berenice Schulte, Christoph Garbers, Juliane Lokau, Ann-Kathrin Vlacil, Juliane Schulz, Anna K. Seoudy, Bernhard Schieffer, Philip Rosenstiel, Marcus Seeger, Matthias Laudes, Stefan Rose-John, Ulf Lützen, Karsten Grote, Stefan Schreiber
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Pharmacology
Subjects:
atherosclerosis
case report
interleukin-6
olamkicept
sgp130Fc
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.758233/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.758233/full

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