Infectious bursal disease virus VP5 triggers host shutoff in a transcription-dependent manner

Infectious bursal disease virus VP5 triggers host shutoff in a transcription-dependent manner

ABSTRACTViruses have evolved intricate mechanisms to evade host antiviral responses and exploit cellular resources by manipulating the expression profile of host genes. During infection, viruses encode proteins with shutoff activity to globally inhibit host protein synthesis, which is an effective s...

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Bibliographic Details
Main Authors: Xinxin Niu, Jinze Han, Mengmeng Huang, Guodong Wang, Yulong Zhang, Wenying Zhang, Hangbo Yu, Mengmeng Xu, Kai Li, Li Gao, Suyan Wang, Yuntong Chen, Hongyu Cui, Yanping Zhang, Changjun Liu, Xiaomei Wang, Yulong Gao, Xiaole Qi
Format: Article
Language:English
Published: American Society for Microbiology 2024-03-01
Series:mBio
Subjects:
host shutoff
nucleocytoplasmic transport
Ran
RanBP1
infectious bursal disease virus
Online Access:https://journals.asm.org/doi/10.1128/mbio.03433-23

Internet

https://journals.asm.org/doi/10.1128/mbio.03433-23

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