Short-chain free fatty acid receptors FFA2/GPR43 and FFA3/GPR41 as new potential therapeutic targets
The deorphanization of the free fatty acid (FFA) receptors FFA1 (GPR40), FFA2 (GPR43), FFA3 (GPR41), GPR84 and GPR120 made clear that the body is capable of recognizing and responding directly to nonesterified fatty acid of virtually any chain length. Colonic fermentation of dietary fiber produces h...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2012-10-01
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Series: | Frontiers in Endocrinology |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fendo.2012.00111/full |