HMGA1 drives chemoresistance in esophageal squamous cell carcinoma by suppressing ferroptosis

HMGA1 drives chemoresistance in esophageal squamous cell carcinoma by suppressing ferroptosis

Abstract Chemotherapy is a primary treatment for esophageal squamous cell carcinoma (ESCC). Resistance to chemotherapeutic drugs is an important hurdle to effective treatment. Understanding the mechanisms underlying chemotherapy resistance in ESCC is an unmet medical need to improve the survival of...

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Bibliographic Details
Main Authors: Jing-Yu Yang, Xin-Yuan Lei, Kai-Yue He, Jin-Rong Guo, Meng-Jie Liu, Jun-Qi Li, Qiu-Tong Li, Zhi-Hao Jiang, Lei Zhang, Dan-Hui Wu, Yu-Jia Li, Qian-Hui Sun, Yong-Ping Jian, Zhi-Xiang Xu
Format: Article
Language:English
Published: Nature Publishing Group 2024-02-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-06467-2

Internet

https://doi.org/10.1038/s41419-024-06467-2

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