The role of endothelial glycocalyx in sepsis
The surface of endothelial cells is filled with various membrane-bound molecules that form the glycocalyx. The endothelial glycocalyx is a surface layer mainly consisted of glycosaminoglycans that include heparan sulfate, chondroitin sulfate, and hyaluronic acid and its core proteins. Previous studi...
Main Authors: | , |
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2019-01-01
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Series: | Bali Journal of Anesthesiology |
Subjects: | |
Online Access: | http://www.bjoaonline.com/article.asp?issn=2549-2276;year=2019;volume=3;issue=1;spage=27;epage=32;aulast=Budi;type=0 |
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author | I Nyoman Budi Hartawan Made Wiryana |
author_facet | I Nyoman Budi Hartawan Made Wiryana |
author_sort | I Nyoman Budi Hartawan |
collection | DOAJ |
description | The surface of endothelial cells is filled with various membrane-bound molecules that form the glycocalyx. The endothelial glycocalyx is a surface layer mainly consisted of glycosaminoglycans that include heparan sulfate, chondroitin sulfate, and hyaluronic acid and its core proteins. Previous studies suggest that endothelial surface glycocalyx shedding could play a role in endothelial dysfunction and inflammation. This article will review the endothelial glycocalyx and its role in sepsis. |
first_indexed | 2024-12-22T10:45:31Z |
format | Article |
id | doaj.art-d990d36046c3409c9d5330fb998a287d |
institution | Directory Open Access Journal |
issn | 2549-2276 |
language | English |
last_indexed | 2024-12-22T10:45:31Z |
publishDate | 2019-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Bali Journal of Anesthesiology |
spelling | doaj.art-d990d36046c3409c9d5330fb998a287d2022-12-21T18:28:57ZengWolters Kluwer Medknow PublicationsBali Journal of Anesthesiology2549-22762019-01-0131273210.15562/bjoa.v3i1.114The role of endothelial glycocalyx in sepsisI Nyoman Budi HartawanMade WiryanaThe surface of endothelial cells is filled with various membrane-bound molecules that form the glycocalyx. The endothelial glycocalyx is a surface layer mainly consisted of glycosaminoglycans that include heparan sulfate, chondroitin sulfate, and hyaluronic acid and its core proteins. Previous studies suggest that endothelial surface glycocalyx shedding could play a role in endothelial dysfunction and inflammation. This article will review the endothelial glycocalyx and its role in sepsis.http://www.bjoaonline.com/article.asp?issn=2549-2276;year=2019;volume=3;issue=1;spage=27;epage=32;aulast=Budi;type=0glycocalyxproteoglycansfunctionshedding |
spellingShingle | I Nyoman Budi Hartawan Made Wiryana The role of endothelial glycocalyx in sepsis Bali Journal of Anesthesiology glycocalyx proteoglycans function shedding |
title | The role of endothelial glycocalyx in sepsis |
title_full | The role of endothelial glycocalyx in sepsis |
title_fullStr | The role of endothelial glycocalyx in sepsis |
title_full_unstemmed | The role of endothelial glycocalyx in sepsis |
title_short | The role of endothelial glycocalyx in sepsis |
title_sort | role of endothelial glycocalyx in sepsis |
topic | glycocalyx proteoglycans function shedding |
url | http://www.bjoaonline.com/article.asp?issn=2549-2276;year=2019;volume=3;issue=1;spage=27;epage=32;aulast=Budi;type=0 |
work_keys_str_mv | AT inyomanbudihartawan theroleofendothelialglycocalyxinsepsis AT madewiryana theroleofendothelialglycocalyxinsepsis AT inyomanbudihartawan roleofendothelialglycocalyxinsepsis AT madewiryana roleofendothelialglycocalyxinsepsis |