The role of endothelial glycocalyx in sepsis

The surface of endothelial cells is filled with various membrane-bound molecules that form the glycocalyx. The endothelial glycocalyx is a surface layer mainly consisted of glycosaminoglycans that include heparan sulfate, chondroitin sulfate, and hyaluronic acid and its core proteins. Previous studi...

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Main Authors: I Nyoman Budi Hartawan, Made Wiryana
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Bali Journal of Anesthesiology
Subjects:
Online Access:http://www.bjoaonline.com/article.asp?issn=2549-2276;year=2019;volume=3;issue=1;spage=27;epage=32;aulast=Budi;type=0
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author I Nyoman Budi Hartawan
Made Wiryana
author_facet I Nyoman Budi Hartawan
Made Wiryana
author_sort I Nyoman Budi Hartawan
collection DOAJ
description The surface of endothelial cells is filled with various membrane-bound molecules that form the glycocalyx. The endothelial glycocalyx is a surface layer mainly consisted of glycosaminoglycans that include heparan sulfate, chondroitin sulfate, and hyaluronic acid and its core proteins. Previous studies suggest that endothelial surface glycocalyx shedding could play a role in endothelial dysfunction and inflammation. This article will review the endothelial glycocalyx and its role in sepsis.
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spelling doaj.art-d990d36046c3409c9d5330fb998a287d2022-12-21T18:28:57ZengWolters Kluwer Medknow PublicationsBali Journal of Anesthesiology2549-22762019-01-0131273210.15562/bjoa.v3i1.114The role of endothelial glycocalyx in sepsisI Nyoman Budi HartawanMade WiryanaThe surface of endothelial cells is filled with various membrane-bound molecules that form the glycocalyx. The endothelial glycocalyx is a surface layer mainly consisted of glycosaminoglycans that include heparan sulfate, chondroitin sulfate, and hyaluronic acid and its core proteins. Previous studies suggest that endothelial surface glycocalyx shedding could play a role in endothelial dysfunction and inflammation. This article will review the endothelial glycocalyx and its role in sepsis.http://www.bjoaonline.com/article.asp?issn=2549-2276;year=2019;volume=3;issue=1;spage=27;epage=32;aulast=Budi;type=0glycocalyxproteoglycansfunctionshedding
spellingShingle I Nyoman Budi Hartawan
Made Wiryana
The role of endothelial glycocalyx in sepsis
Bali Journal of Anesthesiology
glycocalyx
proteoglycans
function
shedding
title The role of endothelial glycocalyx in sepsis
title_full The role of endothelial glycocalyx in sepsis
title_fullStr The role of endothelial glycocalyx in sepsis
title_full_unstemmed The role of endothelial glycocalyx in sepsis
title_short The role of endothelial glycocalyx in sepsis
title_sort role of endothelial glycocalyx in sepsis
topic glycocalyx
proteoglycans
function
shedding
url http://www.bjoaonline.com/article.asp?issn=2549-2276;year=2019;volume=3;issue=1;spage=27;epage=32;aulast=Budi;type=0
work_keys_str_mv AT inyomanbudihartawan theroleofendothelialglycocalyxinsepsis
AT madewiryana theroleofendothelialglycocalyxinsepsis
AT inyomanbudihartawan roleofendothelialglycocalyxinsepsis
AT madewiryana roleofendothelialglycocalyxinsepsis