MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons

MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons

Bone morphogenetic protein (BMP) signaling has emerged as an important regulator of sensory neuron development. Using a three-generation forward genetic screen in mice we have identified Megf8 as a novel modifier of BMP4 signaling in trigeminal ganglion (TG) neurons. Loss of Megf8 disrupts axon guid...

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Bibliographic Details
Main Authors: Caitlin Engelhard, Sarah Sarsfield, Janna Merte, Qiang Wang, Peng Li, Hideyuki Beppu, Alex L Kolodkin, Henry M Sucov, David D Ginty
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-09-01
Series:eLife
Subjects:
BMP
development
trigeminal ganglion
Online Access:https://elifesciences.org/articles/01160

Internet

https://elifesciences.org/articles/01160

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