Chlorinated Guaiane-Type Sesquiterpene Lactones as Cytotoxic Agents against Human Tumor Cells

Chlorinated Guaiane-Type Sesquiterpene Lactones as Cytotoxic Agents against Human Tumor Cells

Guaiane-type sesquiterpene lactones are naturally occurring compounds which have attracted attention due to their array of biological activities. In this study, chlorinated guaianolides <b>1</b>–<b>8</b>, isolated from plants of the genus <i>Centaurea</i>, were ev...

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Bibliographic Details
Main Authors: Francisco Estévez-Sarmiento, Ester Saavedra, Mercedes Ruiz-Estévez, Francisco León, José Quintana, Ignacio Brouard, Francisco Estévez
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
apoptosis
cytotoxicity
caspase
poly(ADP-ribose) polymerase
sesquiterpene lactone
guaianolide
Online Access:https://www.mdpi.com/1422-0067/21/24/9767

Internet

https://www.mdpi.com/1422-0067/21/24/9767

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