The Search for New Antibacterial Agents among 1,2,3-Triazole Functionalized Ciprofloxacin and Norfloxacin Hybrids: Synthesis, Docking Studies, and Biological Activity Evaluation

The Search for New Antibacterial Agents among 1,2,3-Triazole Functionalized Ciprofloxacin and Norfloxacin Hybrids: Synthesis, Docking Studies, and Biological Activity Evaluation

Among all modern antibiotics, fluoroquinolones are well known for their broad spectrums of activity and efficiency toward microorganisms and viruses. However, antibiotic resistance is still a problem, which has encouraged medicinal chemists to modify the initial structures in order to combat resista...

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Bibliographic Details
Main Authors: Halyna Hryhoriv, Illia Mariutsa, Sergiy M. Kovalenko, Victoriya Georgiyants, Lina Perekhoda, Nataliia Filimonova, Olga Geyderikh, Lyudmila Sidorenko
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Scientia Pharmaceutica
Subjects:
fluoroquinolones
ciprofloxacin
norfloxacin
synthesis
antibiotic resistance
molecular docking
Online Access:https://www.mdpi.com/2218-0532/90/1/2

Internet

https://www.mdpi.com/2218-0532/90/1/2

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