Advances in targeting histone deacetylase for treatment of solid tumors

Advances in targeting histone deacetylase for treatment of solid tumors

Abstract Histone deacetylase (HDAC) serves as a critical molecular regulator in the pathobiology of various malignancies and have garnered attention as a viable target for therapeutic intervention. A variety of HDAC inhibitors (HDACis) have been developed to target HDACs. Many preclinical studies ha...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Mu-Qi Shi, Ying Xu, Xin Fu, De-Si Pan, Xian-Ping Lu, Yi Xiao, Yi-Zhou Jiang
Format: Artikel
Sprache:English
Veröffentlicht: BMC 2024-05-01
Schriftenreihe:Journal of Hematology & Oncology
Schlagworte:
Histone deacetylase
Histone deacetylase inhibitor
Solid tumor
Combination therapy
Clinical administration
Online Zugang:https://doi.org/10.1186/s13045-024-01551-8

Online

https://doi.org/10.1186/s13045-024-01551-8

Ähnliche Einträge