MiR-130a is aberrantly overexpressed in adult acute myeloid leukemia with t(8;21) and its suppression induces AML cell death

MiR-130a is aberrantly overexpressed in adult acute myeloid leukemia with t(8;21) and its suppression induces AML cell death

Background: Emerging evidence has revealed that miRNAs can function as oncogenes or tumor suppressor genes in leukemia. The ectopic expression of miR-130a has been reported in chronic leukemia, but our understanding of the biological implications of miR-130a expression remains incomplete. Methods: W...

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Bibliographic Details
Main Authors: Chao Ding, Su-Ning Chen, Roderick A. F. Macleod, Hans G. Drexler, Stefan Nagel, De-Pei Wu, Ai-Ning Sun, Hai-Ping Dai
Format: Article
Language:English
Published: Upsala Medical Society 2018-01-01
Series:Upsala Journal of Medical Sciences
Subjects:
Acute myeloid leukemia
miR-130a
t(8;21)
outcome
overexpression
Online Access:http://dx.doi.org/10.1080/03009734.2018.1440037

Internet

http://dx.doi.org/10.1080/03009734.2018.1440037

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