Clinical, gut microbial and neural effects of a probiotic add-on therapy in depressed patients: a randomized controlled trial

Abstract A promising new treatment approach for major depressive disorder (MDD) targets the microbiota-gut-brain (MGB) axis, which is linked to physiological and behavioral functions affected in MDD. This is the first randomized controlled trial to determine whether short-term, high-dose probiotic s...

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Bibliographic Details
Main Authors: Anna-Chiara Schaub, Else Schneider, Jorge F. Vazquez-Castellanos, Nina Schweinfurth, Cedric Kettelhack, Jessica P. K. Doll, Gulnara Yamanbaeva, Laura Mählmann, Serge Brand, Christoph Beglinger, Stefan Borgwardt, Jeroen Raes, André Schmidt, Undine E. Lang
Format: Article
Language:English
Published: Nature Publishing Group 2022-06-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-022-01977-z