Single Nucleus Sequencing of Human Colon Myenteric Plexus–Associated Visceral Smooth Muscle Cells, Platelet Derived Growth Factor Receptor Alpha Cells, and Interstitial Cells of Cajal

Single Nucleus Sequencing of Human Colon Myenteric Plexus–Associated Visceral Smooth Muscle Cells, Platelet Derived Growth Factor Receptor Alpha Cells, and Interstitial Cells of Cajal

Background and Aims: Smooth muscle cells (SMCs), interstitial cells of Cajal (ICCs), and platelet-derived growth factor receptor alpha (PDGFRα+) cells (PαCs) form a functional syncytium in the bowel known as the “SIP syncytium.” The SIP syncytium works in concert with the enteric nervous system (ENS...

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Bibliographic Details
Main Authors: Sabine Schneider, Sohaib K. Hashmi, A. Josephine Thrasher, Deepika R. Kothakapa, Christina M. Wright, Robert O. Heuckeroth
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Gastro Hep Advances
Subjects:
SIP Syncytium
Smooth Muscle
Interstitial Cells of Cajal
PDGFRA
Single-Nucleus RNA Sequencing
Online Access:http://www.sciencedirect.com/science/article/pii/S2772572322002060

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http://www.sciencedirect.com/science/article/pii/S2772572322002060

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