The CTRP3-AdipoR2 Axis Regulates the Development of Experimental Autoimmune Encephalomyelitis by Suppressing Th17 Cell Differentiation

The CTRP3-AdipoR2 Axis Regulates the Development of Experimental Autoimmune Encephalomyelitis by Suppressing Th17 Cell Differentiation

C1q/TNF-related proteins (CTRP) including CTRP3 are a group of secreted proteins which have a complement C1q-like domain in common, and play versatile roles in lipid metabolism, inflammation, tumor metastasis and bone metabolism. Previously, we showed that the expression of C1qtnf3, encoding CTRP3,...

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Bibliographic Details
Main Authors: Masanori A. Murayama, Hsi-Hua Chi, Mako Matsuoka, Takahiro Ono, Yoichiro Iwakura
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Immunology
Subjects:
CTRP3
Th17 cells
AdipoR2
EAE
autoimmune diseases
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.607346/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.607346/full

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