Evolution after introduction of a novel metabolic pathway consistently leads to restoration of wild-type physiology.
Organisms cope with physiological stressors through acclimatizing mechanisms in the short-term and adaptive mechanisms over evolutionary timescales. During adaptation to an environmental or genetic perturbation, beneficial mutations can generate numerous physiological changes: some will be novel wit...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-04-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC3616920?pdf=render |