ASCARIS: Positional feature annotation and protein structure-based representation of single amino acid variations

ASCARIS: Positional feature annotation and protein structure-based representation of single amino acid variations

Background: Genomic variations may cause deleterious effects on protein functionality and perturb biological processes. Elucidating the effects of variations is critical for developing novel treatment strategies for diseases of genetic origin. Computational approaches have been aiding the work in th...

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Bibliographic Details
Main Authors: Fatma Cankara, Tunca Doğan
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Single amino acid variations
Biomolecular representations
Protein sequence annotations
Protein domains
Bioinformatics tools/models
Variant effect prediction
Online Access:http://www.sciencedirect.com/science/article/pii/S200103702300329X

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http://www.sciencedirect.com/science/article/pii/S200103702300329X

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