Characterization of the Intra-tumoral B Cell Immunoglobulin Repertoire Is of Prognostic Value for Esophageal Squamous Cell Carcinoma

Characterization of the Intra-tumoral B Cell Immunoglobulin Repertoire Is of Prognostic Value for Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell carcinomas (ESCC) is a highly heterogeneous malignancy that is among the leading cause of cancer-related death worldwide. B cells play pivotal roles in the immune defense system and cancer progression and regression, yet the repertoire of tumor infiltrating B cells (TIBs) an...

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Bibliographic Details
Main Authors: Zhizhong Wang, Zhenguo Cheng, Shuangshuang Lu, Louisa S. Chard Dunmall, Jun Wang, Yongjun Guo, Yaohe Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
ESCC
TIBs
immunoglobulin repertoire
IgG2-producing plasma cells
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.896627/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.896627/full

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