C-Mannosylation Enhances the Structural Stability of Human RNase 2

Summary: C-Mannosylation is a relatively rare form of protein glycosylation involving the attachment of an α-mannopyranosyl residue to C-2 of the indole moiety of the amino acid tryptophan. This type of linkage was initially discovered in RNase 2 from human urine but later confirmed to be present in...

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Bibliographic Details
Main Authors: Martin Frank, Daniela Beccati, Bas R. Leeflang, Johannes F.G. Vliegenthart
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220305599