Icariin-Loaded Hydrogel Regulates Bone Marrow Mesenchymal Stem Cell Chondrogenic Differentiation and Promotes Cartilage Repair in Osteoarthritis

Icariin-Loaded Hydrogel Regulates Bone Marrow Mesenchymal Stem Cell Chondrogenic Differentiation and Promotes Cartilage Repair in Osteoarthritis

Intra-articular injection of mesenchymal stem cells is a potential therapeutic strategy for cartilage protection and symptom relief for osteoarthritis (OA). However, controlling chondrogenesis of the implanted cells in the articular cavity remains a challenge. In this study, hydrogels containing dif...

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Bibliographic Details
Main Authors: Yuefeng Zhu, Le Ye, Xiaoxi Cai, Zuhao Li, Yongqian Fan, Fengjian Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
icariin
hydrogel
BMSCs
osteoarthritis
cartilage repair
pain relief
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.755260/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.755260/full

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