Effects of prophylactic ibuprofen and paracetamol administration on the immunogenicity and reactogenicity of the 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugated vaccine (PHiD-CV) co-administered with DTPa-combined vaccines in children: An open-label, randomized, controlled, non-inferiority trial

Effects of prophylactic ibuprofen and paracetamol administration on the immunogenicity and reactogenicity of the 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugated vaccine (PHiD-CV) co-administered with DTPa-combined vaccines in children: An open-label, randomized, controlled, non-inferiority trial

Prophylactic paracetamol administration impacts vaccine immune response; this study (www.clinicaltrials.gov: NCT01235949) is the first to assess PHiD-CV immunogenicity following prophylactic ibuprofen administration. In this phase IV, multicenter, open-label, randomized, controlled, non-inferiority...

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Bibliographic Details
Main Authors: Oana Falup-Pecurariu, Sorin C. Man, Mihai L. Neamtu, Gratiana Chicin, Ginel Baciu, Carmen Pitic, Alexandra C. Cara, Andrea E. Neculau, Marin Burlea, Ileana L. Brinza, Cristina N. Schnell, Valentina Sas, Valeriu V. Lupu, Nancy François, Kristien Swinnen, Dorota Borys
Format: Article
Language:English
Published: Taylor & Francis Group 2017-03-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
fever
ibuprofen
paracetamol
prophylaxis
vaccine
10-valent pneumococcal conjugate
Online Access:http://dx.doi.org/10.1080/21645515.2016.1223001

Internet

http://dx.doi.org/10.1080/21645515.2016.1223001

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