Ceramide synthesis regulates biogenesis and packaging of exosomal MALAT1 from adipose derived stem cells, increases dermal fibroblast migration and mitochondrial function

Ceramide synthesis regulates biogenesis and packaging of exosomal MALAT1 from adipose derived stem cells, increases dermal fibroblast migration and mitochondrial function

Abstract Background The function of exosomes, small extracellular vesicles (sEV) secreted from human adipose-derived stem cells (ADSC), is becoming increasingly recognized as a means of transferring the regenerative power of stem cells to injured cells in wound healing. Exosomes are rich in ceramide...

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Bibliographic Details
Main Authors: Xaioyuan Kong, Niketa A. Patel, Charles E. Chalfant, Denise R. Cooper
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Cell Communication and Signaling
Subjects:
Adipose-derived stem cells
Cell migration scratch assay
Ceramide
Exosomes
Extracellular vesicles
Human dermal fibroblasts
Online Access:https://doi.org/10.1186/s12964-022-00900-9

Internet

https://doi.org/10.1186/s12964-022-00900-9

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