Effective suppression of Dengue fever virus in mosquito cell cultures using retroviral transduction of hammerhead ribozymes targeting the viral genome

Effective suppression of Dengue fever virus in mosquito cell cultures using retroviral transduction of hammerhead ribozymes targeting the viral genome

<p>Abstract</p> <p>Outbreaks of Dengue impose a heavy economic burden on developing countries in terms of vector control and human morbidity. Effective vaccines against all four serotypes of Dengue are in development, but population replacement with transgenic vectors unable to tra...

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Bibliographic Details
Main Authors: Mohammed Ahmed, Higgs Stephen, Davey Robert A, Kolokoltsov Andrey, Balaraman Velmurugan, Fraser Tresa, Keith James, Nawtaisong Pruksa, Rongsriyam Yupha, Komalamisra Narumon, Fraser Malcolm J
Format: Article
Language:English
Published: BMC 2009-06-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/6/1/73

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http://www.virologyj.com/content/6/1/73

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