P16 and p53 play distinct roles in different subtypes of breast cancer.

P16 and p53 play distinct roles in different subtypes of breast cancer.

Breast cancers are heterogeneous and complex diseases, and subtypes of breast cancers may involve unique molecular mechanisms. The p16(INK4a) and p53 pathways are two of the major pathways involved in control of the cell cycle. They also play key roles in tumorigenesis. However, whether the roles of...

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Bibliographic Details
Main Authors: Ming Shan, Xianyu Zhang, Xiaolong Liu, Yu Qin, Tong Liu, Yang Liu, Ji Wang, Zhenbin Zhong, Youxue Zhang, Jingshu Geng, Da Pang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3795768?pdf=render

Internet

http://europepmc.org/articles/PMC3795768?pdf=render

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