Tangshen formula attenuates diabetic renal injuries by upregulating autophagy via inhibition of PLZF expression.

The Chinese herbal granule Tangshen Formula (TSF) has been proven to decrease proteinuria and improve estimated glomerular filtration rate (eGFR) in diabetic kidney disease (DKD) patients. However, the underlying mechanism of TSF on treatment of diabetic nephropathy (DN) remains unclear. The present...

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Bibliographic Details
Main Authors: Hailing Zhao, Xin Li, Tingting Zhao, Haojun Zhang, Meihua Yan, Xi Dong, Pengmin Chen, Liang Ma, Ping Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5300159?pdf=render