Pulmonary Hypertension-Associated Right Ventricular Cardiomyocyte Remodelling Reduces Treprostinil Function

Pulmonary Hypertension-Associated Right Ventricular Cardiomyocyte Remodelling Reduces Treprostinil Function

(1) Pulmonary hypertension (PH)-associated right ventricular (RV) failure is linked to a reduction in pulmonary vasodilators. Treprostinil has shown effectiveness in PAH patients with cardiac decompensation, hinting at potential cardiac benefits. We investigated treprostinil’s synergy with isoprenal...

Full description

Bibliographic Details
Main Authors: Aleksandra Judina, Marili Niglas, Vladislav Leonov, Nicholas S. Kirkby, Ivan Diakonov, Peter T. Wright, Lan Zhao, Jane A. Mitchell, Julia Gorelik
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Cells
Subjects:
pulmonary hypertension
right ventricle
cardiomyocytes
treprostinil
sarcomere shortening
cell length deflection
Online Access:https://www.mdpi.com/2073-4409/12/23/2764

Internet

https://www.mdpi.com/2073-4409/12/23/2764

Similar Items