Perfluorocarbon Nanoemulsions with Fluorous Chlorin-Type Photosensitizers for Antitumor Photodynamic Therapy in Hypoxia

Perfluorocarbon Nanoemulsions with Fluorous Chlorin-Type Photosensitizers for Antitumor Photodynamic Therapy in Hypoxia

The efficacy of photodynamic therapy (PDT) strictly depends on the availability of molecular oxygen to trigger the light-induced generation of reactive species. Fluorocarbons have an increased ability to dissolve oxygen and are attractive tools for gas delivery. We synthesized three fluorous derivat...

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Bibliographic Details
Main Authors: Minh Tuan Nguyen, Elizaveta V. Guseva, Aida N. Ataeva, Andrey L. Sigan, Anna V. Shibaeva, Maria V. Dmitrieva, Ivan D. Burtsev, Yulia L. Volodina, Alexandra S. Radchenko, Anton E. Egorov, Alexey A. Kostyukov, Pavel V. Melnikov, Nikolai D. Chkanikov, Vladimir A. Kuzmin, Alexander A. Shtil, Alina A. Markova
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
perfluorocarbons
chlorins
nanoemulsion
tumor cells
hypoxia
phototoxicity
Online Access:https://www.mdpi.com/1422-0067/24/9/7995

Internet

https://www.mdpi.com/1422-0067/24/9/7995

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