A label free chemoproteomic-based platform to disclose cannabidiol molecular mechanism of action on chronic myelogenous leukemia cancer cells

A label free chemoproteomic-based platform to disclose cannabidiol molecular mechanism of action on chronic myelogenous leukemia cancer cells

The discovery of the interactome of cannabidiol (CBD), a non-psychoactive cannabinoid from Cannabis sativa L., has been here performed on chronic myelogenous leukemia cancer cells, using an optimized chemo-proteomic stage, which links Drug Affinity Responsive Target Stability with Limited Proteolysi...

Full description

Bibliographic Details
Main Authors: Sara Ceccacci, Lorenzo Corsi, Lucio Spinelli, Clarissa Caroli, Matilde Marani, Lisa Anceschi, Matteo Mozzicafreddo, Federica Pellati, Maria Chiara Monti
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Heliyon
Subjects:
Cannabidiol
Chronic myelogenous leukemia
Drug Affinity Responsive Target Stability
Limited proteolysis
Chemo-proteomics
Mass spectrometry
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024002275

Internet

http://www.sciencedirect.com/science/article/pii/S2405844024002275

Similar Items