GCLiPP: global crosslinking and protein purification method for constructing high-resolution occupancy maps for RNA binding proteins

GCLiPP: global crosslinking and protein purification method for constructing high-resolution occupancy maps for RNA binding proteins

Abstract GCLiPP is a global RNA interactome capture method that detects RNA-binding protein (RBP) occupancy transcriptome-wide. GCLiPP maps RBP-occupied sites at a higher resolution than phase separation-based techniques. GCLiPP sequence tags correspond with known RBP binding sites and are enriched...

Full description

Bibliographic Details
Main Authors: Wandi S. Zhu, Adam J. Litterman, Harshaan S. Sekhon, Robin Kageyama, Maya M. Arce, Kimberly E. Taylor, Wenxue Zhao, Lindsey A. Criswell, Noah Zaitlen, David J. Erle, K. Mark Ansel
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Genome Biology
Subjects:
Post-transcriptional regulation
RNA-binding proteins (RBP)
T cells
Cis-regulatory elements
Online Access:https://doi.org/10.1186/s13059-023-03125-2

Internet

https://doi.org/10.1186/s13059-023-03125-2

Similar Items