GCLiPP: global crosslinking and protein purification method for constructing high-resolution occupancy maps for RNA binding proteins

GCLiPP: global crosslinking and protein purification method for constructing high-resolution occupancy maps for RNA binding proteins

Abstract GCLiPP is a global RNA interactome capture method that detects RNA-binding protein (RBP) occupancy transcriptome-wide. GCLiPP maps RBP-occupied sites at a higher resolution than phase separation-based techniques. GCLiPP sequence tags correspond with known RBP binding sites and are enriched...

Повний опис

Бібліографічні деталі
Автори: Wandi S. Zhu, Adam J. Litterman, Harshaan S. Sekhon, Robin Kageyama, Maya M. Arce, Kimberly E. Taylor, Wenxue Zhao, Lindsey A. Criswell, Noah Zaitlen, David J. Erle, K. Mark Ansel
Формат: Стаття
Мова:English
Опубліковано: BMC 2023-12-01
Серія:Genome Biology
Предмети:
Post-transcriptional regulation
RNA-binding proteins (RBP)
T cells
Cis-regulatory elements
Онлайн доступ:https://doi.org/10.1186/s13059-023-03125-2

Інтернет

https://doi.org/10.1186/s13059-023-03125-2

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