A Novel Recombinant FAdV-4 Virus with Fiber of FAdV-8b Provides Efficient Protection against Both FAdV-4 and FAdV-8b

A Novel Recombinant FAdV-4 Virus with Fiber of FAdV-8b Provides Efficient Protection against Both FAdV-4 and FAdV-8b

Since 2015, the outbreaks of hydropericardium-hepatitis syndrome (HHS) and inclusion body hepatitis (IBH) caused by the highly pathogenic serotype 4 fowl adenovirus (FAdV-4) and serotype 8 fowl adenovirus (FAdV-8), respectively, have caused huge economic losses to the poultry industry. Although seve...

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Bibliographic Details
Main Authors: Hao Lu, Quan Xie, Wei Zhang, Jianjun Zhang, Weikang Wang, Mingjun Lian, Zhehong Zhao, Dan Ren, Songhua Xie, Yun Lin, Tuofan Li, Yaru Mu, Zhimin Wan, Hongxia Shao, Aijian Qin, Jianqiang Ye
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Viruses
Subjects:
FAdV-4
FAdV-8
CRISPR-Cas9
recombinant virus
pathogenicity
inactivated vaccine
Online Access:https://www.mdpi.com/1999-4915/14/2/376

Internet

https://www.mdpi.com/1999-4915/14/2/376

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