Additional cytosine inside mitochondrial C-tract D-loop as a progression risk factor in oral precancer cases
Introduction: Alterations inside Polycytosine tract (C-tract) of mitochondrial DNA (mtDNA) have been described in many different tumor types. The Poly-Cytosine region is located within the mtDNA D-loop region which acts as point of mitochondrial replication origin. A suggested pathogenesis is that i...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-01-01
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Series: | Journal of Oral Biology and Craniofacial Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2212426814000062 |