TlcMHCpan: A Novel Deep Learning Model for Enhanced Pan-Specific Prediction of Peptide-HLA Binding

TlcMHCpan: A Novel Deep Learning Model for Enhanced Pan-Specific Prediction of Peptide-HLA Binding

The interaction between Human Leukocyte Antigens (HLA) and peptides is key in cellular immunology and crucial for the development of the immune system and peptide-based drug design. Currently, in the field of machine learning for predicting peptide-HLA (pHLA) binding, the mainstream methods involve...

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Bibliographic Details
Main Authors: Xin Peng, Donghong Yang, Yiming Zhou, Shenglan Peng
Format: Article
Language:English
Published: IEEE 2024-01-01
Series:IEEE Access
Subjects:
Peptide-HLA binding
transformer
LSTM
self-attention
Online Access:https://ieeexplore.ieee.org/document/10781337/

Internet

https://ieeexplore.ieee.org/document/10781337/

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