SLC38A5 aggravates DC-mediated psoriasiform skin inflammation via potentiating lysosomal acidification

SLC38A5 aggravates DC-mediated psoriasiform skin inflammation via potentiating lysosomal acidification

Summary: Amino acid (aa) metabolism is closely correlated with the pathogenesis of psoriasis; however, details on aa transportation during this process are barely known. Here, we find that SLC38A5, a sodium-dependent neutral aa transporter that counter-transports protons, is markedly upregulated in...

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Bibliographic Details
Main Authors: Leqing Zhu, Xichun Xia, Guangqiang Li, Chuyun Zhu, Qingqing Li, Baocheng Wang, Nan-Xi Shi, Zhiwei Lei, Shuxian Yang, Zhanpeng Zhang, Haishan Li, Jingyi Tan, Zonghua Liu, Qiong Wen, Hui Zhong, Xue-Jia Lin, Guodong Sun, Xiucong Bao, Qian Wang, Liehua Deng, Lianghua Bin, Guangchao Cao, Zhinan Yin
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472300921X

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http://www.sciencedirect.com/science/article/pii/S221112472300921X

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