Prolonged Administration of <i>Rudgea viburnoides</i> (Cham.) Benth. Prevents Impairment of Redox Status, Renal Dysfunction, and Cardiovascular Damage in 2K1C-Hypertensive Rats by Inhibiting ACE Activity and NO-GMPC Pathway Activation

Prolonged Administration of <i>Rudgea viburnoides</i> (Cham.) Benth. Prevents Impairment of Redox Status, Renal Dysfunction, and Cardiovascular Damage in 2K1C-Hypertensive Rats by Inhibiting ACE Activity and NO-GMPC Pathway Activation

<i>Rudgea viburnoides</i> is widely found in the Brazilian Cerrado, and commonly used in Brazilian folk medicine. In this study, we evaluated the effects of prolonged administration of the aqueous extract from <i>R. viburnoides</i> leaves (AERV) on impaired redox status, rena...

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Bibliographic Details
Main Authors: Fernanda Viana Paulin, Rhanany Alan Calloi Palozi, Bethânia Rosa Lorençone, Arthur Ladeira Macedo, Lucas Pires Guarnier, Cleide Adriane Signor Tirloni, Paulo Vitor Moreira Romão, Arquimedes Gasparotto Junior, Denise Brentan Silva
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Pharmaceutics
Subjects:
antihypertensive
antioxidant
cardioprotective
diuretic
renoprotective
iridoid
Online Access:https://www.mdpi.com/1999-4923/13/10/1579

Internet

https://www.mdpi.com/1999-4923/13/10/1579

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