Human Cytotoxicity, Hemolytic Activity, Anti-Inflammatory Activity and Aqueous Solubility of Ibuprofen-Based Ionic Liquids

Human Cytotoxicity, Hemolytic Activity, Anti-Inflammatory Activity and Aqueous Solubility of Ibuprofen-Based Ionic Liquids

Ionic liquids (ILs) are a potential solution to the general problem of low solubility, polymorphism and low bioavailability of active pharmaceutical ingredients (APIs). In this work, we report on the synthesis of three pharmaceutically active ILs (API-ILs) based on ibuprofen, one of the most commonl...

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Bibliographic Details
Main Authors: Joana C. Bastos, Nicole S. M. Vieira, Maria Manuela Gaspar, Ana B. Pereiro, João M. M. Araújo
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Sustainable Chemistry
Subjects:
ionic liquids
ibuprofen
bioavailability
cytotoxicity
HepG2
Caco-2
Online Access:https://www.mdpi.com/2673-4079/3/3/23

Internet

https://www.mdpi.com/2673-4079/3/3/23

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