A portable immunosensor provides sensitive and rapid detection of Borrelia burgdorferi antigen in spiked blood

Abstract There are no assays for detecting B. burgdorferi antigen in blood of infected Lyme disease individuals. Here, we provide proof-of-principle evidence that we can quantify B. burgdorferi antigen in spiked blood using a portable smartphone-based fluorescence microscope that measures immunoaggl...

Full description

Bibliographic Details
Main Authors: Sangsik Kim, Kamalika Samanta, Brandon T. Nguyen, Samantha Mata-Robles, Luciana Richer, Jeong-Yeol Yoon, Maria Gomes-Solecki
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-34108-9