LncRNA CARMN overexpression promotes prognosis and chemosensitivity of triple negative breast cancer via acting as miR143-3p host gene and inhibiting DNA replication

LncRNA CARMN overexpression promotes prognosis and chemosensitivity of triple negative breast cancer via acting as miR143-3p host gene and inhibiting DNA replication

Abstract Background Triple negative breast cancer (TNBC) is a subtype of breast cancer with poor prognosis and lack of effective treatment target. Here we screened differentially expressed lncRNAs through bioinformatics analysis and identified CARMN as a downregulated lncRNA which is lowest expresse...

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Bibliographic Details
Main Authors: Xiaonan Sheng, Huijuan Dai, Yueyao Du, Jing Peng, Rui Sha, Fan Yang, Liheng Zhou, Yanping Lin, Shuguang Xu, Yifan Wu, Wenjin Yin, Jinsong Lu
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
lncRNA
miRNA
Triple negative breast cancer
Neoadjuvant chemotherapy
Predictive and prognostic biomarker
Host gene
Online Access:https://doi.org/10.1186/s13046-021-02015-4

Internet

https://doi.org/10.1186/s13046-021-02015-4

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