Delivery of the Sox9 gene promotes chondrogenic differentiation of human umbilical cord blood-derived mesenchymal stem cells in an in vitro model

Delivery of the Sox9 gene promotes chondrogenic differentiation of human umbilical cord blood-derived mesenchymal stem cells in an in vitro model

SRY-related high-mobility-group box 9 (Sox9) gene is a cartilage-specific transcription factor that plays essential roles in chondrocyte differentiation and cartilage formation. The aim of this study was to investigate the feasibility of genetic delivery of Sox9 to enhance chondrogenic differentiati...

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Bibliographic Details
Main Authors: Z.H. Wang, X.L. Li, X.J. He, B.J. Wu, M. Xu, H.M. Chang, X.H. Zhang, Z. Xing, X.H. Jing, D.M. Kong, X.H. Kou, Y.Y. Yang
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2014-04-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Genetic modification
Tissue engineering
Stem cells
Sox9
Chondrogenesis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000400279&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000400279&lng=en&tlng=en

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