A new approach to characterize cardiac sodium storage by combining fluorescence photometry and magnetic resonance imaging in small animal research

A new approach to characterize cardiac sodium storage by combining fluorescence photometry and magnetic resonance imaging in small animal research

Abstract Cardiac myocyte sodium (Na+) homoeostasis is pivotal in cardiac diseases and heart failure. Intracellular Na+ ([Na+]i) is an important regulator of excitation–contraction coupling and mitochondrial energetics. In addition, extracellular Na+ ([Na+]e) and its water-free storage trigger collag...

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Bibliographic Details
Main Authors: Martin Christa, Franziska Dithmar, Tobias Weinaus, Michael Kohlhaas, Anahi-Paula Arias-Loza, Michelle Hofmann, Ibrahim A. Elabyad, Fabian T. Gutjahr, Christoph Maack, Wolfgang R. Bauer
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-52377-w

Internet

https://doi.org/10.1038/s41598-024-52377-w

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