Structural basis for the self-recognition of sDSCAM in Chelicerata

Abstract To create a functional neural circuit, neurons develop a molecular identity to discriminate self from non-self. The invertebrate Dscam family and vertebrate Pcdh family are implicated in determining synaptic specificity. Recently identified in Chelicerata, a shortened Dscam (sDscam) has bee...

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Bibliographic Details
Main Authors: Jie Cheng, Yamei Yu, Xingyu Wang, Xi Zheng, Ting Liu, Daojun Hu, Yongfeng Jin, Ying Lai, Tian-Min Fu, Qiang Chen
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38205-1