Bioinformatic analysis reveals potential relationship between chondrocyte senescence and protein glycosylation in osteoarthritis pathogenesis

Bioinformatic analysis reveals potential relationship between chondrocyte senescence and protein glycosylation in osteoarthritis pathogenesis

Osteoarthritis (OA) is the most common degenerative and progressive joint disease. Cellular senescence is an irreversible cell cycle arrest progressive with age, while protein glycosylation is the most abundant post-translational modification, regulating various cellular and biological pathways. The...

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Bibliographic Details
Main Authors: Makoto Yoshimoto, Koki Sadamori, Kazuya Tokumura, Yuki Tanaka, Kazuya Fukasawa, Eiichi Hinoi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Endocrinology
Subjects:
osteoarthritis
chondrocyte
cellular senescence
protein glycosylation
gene expression omnibus
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1153689/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1153689/full

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