Transcriptome profiling of osteoclast subsets associated with arthritis: A pathogenic role of CCR2hi osteoclast progenitors

Transcriptome profiling of osteoclast subsets associated with arthritis: A pathogenic role of CCR2hi osteoclast progenitors

IntroductionThe existence of different osteoclast progenitor (OCP) subsets has been confirmed by numerous studies. However, pathological inflammation-induced osteoclastogenesis remains incompletely understood. Detailed characterization of OCP subsets may elucidate the pathophysiology of increased os...

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Bibliographic Details
Main Authors: Maša Filipović, Darja Flegar, Sara Aničić, Dino Šisl, Tomislav Kelava, Nataša Kovačić, Alan Šućur, Danka Grčević
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
RNA sequencing
mouse arthritis
chemokine receptor
osteoclast differentiation
osteoclast progenitor (OCP)
gene expression
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.994035/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.994035/full

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