FTO-mediated m6A demethylation of pri-miR-3591 alleviates osteoarthritis progression

FTO-mediated m6A demethylation of pri-miR-3591 alleviates osteoarthritis progression

Abstract Objectives Increasing evidence have demonstrated the N6-methyladenosine (m6A) plays critical roles in osteoarthritis (OA) progression, but the role of m6A in OA has not been completely illuminated. Herein, we investigated the function and underlying mechanism of m6A demethylase fat mass and...

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Bibliographic Details
Main Authors: Wengang Liu, Tao Jiang, Wei Zheng, Jiayuan Zhang, Anan Li, Chao Lu, Zhaowei Lin
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Arthritis Research & Therapy
Subjects:
Osteoarthritis
N6-methyladenosine (m6A)
FTO
miR-3591-5p
PRKAA2
Online Access:https://doi.org/10.1186/s13075-023-03035-5

Internet

https://doi.org/10.1186/s13075-023-03035-5

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