Plaques Formed by Mutagenized Viral Populations Have Elevated Coinfection Frequencies
ABSTRACT The plaque assay is a common technique used to measure virus concentrations and is based upon the principle that each plaque represents a single infectious unit. As such, the number of plaques is expected to correlate linearly with the virus dilution plated, and each plaque should be formed...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2017-05-01
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Series: | mBio |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mBio.02020-16 |