Smad2/3/4 Pathway Contributes to TGF-β-Induced MiRNA-181b Expression to Promote Gastric Cancer Metastasis by Targeting Timp3

Smad2/3/4 Pathway Contributes to TGF-β-Induced MiRNA-181b Expression to Promote Gastric Cancer Metastasis by Targeting Timp3

Background/Aims: Transforming growth factor beta (TGF-β) plays a major role in tumorigenesis. MicroRNA-181b (miRNA-181b) is a multifaceted miRNA that has been implicated in many cellular processes such as cell fate determination and cellular invasion. This study aimed to confirm the relationship of...

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Bibliographic Details
Main Authors: Qi Zhou, Xiao Zheng, Lujun Chen, Bin Xu, Xin Yang, Jingting Jiang, Changping Wu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Gastric cancer
TGF-β
EMT
MiRNA-181b
Smad4
Timp3
Online Access:http://www.karger.com/Article/FullText/445638

Internet

http://www.karger.com/Article/FullText/445638

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